From time-unspecified measurements to chronobiological specialties such as chronomedicine and chronoastrobiology: Challeges for manufacturing

F. Halberg, Germaine G Cornelissen-Guillaume, Y. Watanabe, J. Siegelova, B. Fiser

Research output: Contribution to journalArticlepeer-review

Abstract

The past half-century has provided the designs implemented first by self-measurements and desk computations and eventually the automatic methods. Biotelemetry for humans is now available on the one hand with more and more sophisticated pacemakers, cardioverters and defibrillators as well as drug pumps on the therapeutic side. Among diagnostic devices, there are implanted heart rate monitors and more ambitious hemodynamic analyzers that record, with heart rate, also blood pressure, albeit as yet only on the right side of the circulation. The tasks on hand are, first, to improve the diagnostic devices to the point where they detect the earliest risk elevation rather than only overt disease; second, to render the therapeutic devices capable of preventive treatment and, third, to close the loop between the aforementioned devices to render preventive treatment automatic or at least self-implementable by the subject concerned.

Original languageEnglish (US)
Pages (from-to)35-44
Number of pages10
JournalScripta Medica Facultatis Medicae Universitatis Brunensis Masarykianae
Volume73
Issue number1
StatePublished - Jan 1 2000

Keywords

  • Chrobiology
  • Chronobioastronomy
  • Chronomedicine
  • Halberg cosinor analysis

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