Freshly fractured crystalline silica induces activator protein-1 activation through ERKs and p38 MAPK

Keyphrases

• Silica 100%
• Activator protein-1 (AP-1) 100%
• Extracellular Regulated Protein Kinases 100%
• Crystalline Silica 100%
• P38 Mitogen-activated Protein Kinase (p38 MAPK) 100%
• Transgenic Mice 20%
• Oncogenesis 20%
• Rat Lung 20%
• Lung Epithelial Cells 20%
• Fold Increase 20%
• Cell Proliferation 10%
• Cell Differentiation 10%
• Phosphorylation 10%
• Family Members 10%
• In Vitro Model 10%
• Signal Transduction Pathway 10%
• Multiple Genes 10%
• Dose Effect 10%
• In Vivo Model 10%
• Epidermal Cells 10%
• Mitogen-activated Protein Kinase 10%
• Kinase Cascade 10%
• Kinase Family 10%
• JB6 Cells 10%
• Neoplastic Transformation 10%
• Transactivation 10%
• Luciferase Reporter 10%
• Epithelial Cell Line 10%
• SB203580 10%
• PD98059 10%
• Cell Inflammation 10%
• Intratracheal Administration 10%
• Cultured Cell Lines 10%

Medicine and Dentistry

• Mitogen Activated Protein Kinase P38 100%
• Transcription Factor AP 1 100%
• Synaptophysin 100%
• Protein Kinases 100%
• Silicon Dioxide 100%
• Cell Line 27%
• Transgenic Mouse 18%
• Carcinogenesis 18%
• In Vitro 9%
• Epithelial Cell 9%
• Cell Proliferation 9%
• Signal Transduction Pathway 9%
• Intratracheal Drug Administration 9%
• 2 (2 Amino 3 Methoxyphenyl)chromone 9%
• SB 203580 9%
• Epithelial Cell Line 9%
• Cell Culture 9%
• Mitogen-Activated Protein Kinase 9%
• Luciferase 9%
• Transactivation 9%

Pharmacology, Toxicology and Pharmaceutical Science

• Silicon Dioxide 100%
• Transcription Factor AP 1 100%
• Mitogen Activated Protein Kinase P38 100%
• Protein Kinases 100%
• Synaptophysin 100%
• Mouse 18%
• Transgenic Mouse 18%
• Carcinogenesis 18%
• Mitogen Activated Protein Kinase 9%
• 2 (2 Amino 3 Methoxyphenyl)chromone 9%
• SB 203580 9%
• Inflammation 9%
• Luciferase 9%