Free thyroxine levels in critically ill patients. A comparison of currently available assays

M. F. Slag, J. E. Morley, M. K. Elson, K. R. Labrosse, T. W. Crowson, frank q Nuttall, R. B. Shafer

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Two indices of free thyroxin (T4) and four methods of free T4 measurement were compared in 85 patients with acute illness, hospitalized in intensive care units. All of the methods of free T4 measurement in critical illness were nonspecific, and two of the methods failed to suggest hypothyroidism in two patients with primary hypothyroidism and another associated critical illness. Since the ideal screening test should be both sensitive and specific, all tests for free T4 used in this study should be interpreted with caution in severely ill patients.

Original languageEnglish (US)
Pages (from-to)2702-2706
Number of pages5
JournalJournal of the American Medical Association
Volume246
Issue number23
DOIs
StatePublished - Dec 1 1981
Externally publishedYes

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