Fragile X Tremor/Ataxia Syndrome: Blame the Messenger!

Maurice S. Swanson, Harry T. Orr

Research output: Contribution to journalShort surveypeer-review

15 Scopus citations


rCGG repeats in premutant alleles of the fragile X gene (FMR1) cause neurodegeneration in Drosophila and are thought to cause fragile X-associated tremor/ataxia syndrome in humans. Two reports in this issue of Neuron (Jin et al. and Sofola et al.) present data indicating a disease mechanism involving disruption of RNA-binding protein function.

Original languageEnglish (US)
Pages (from-to)535-537
Number of pages3
Issue number4
StatePublished - Aug 16 2007


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