Four-fraction radiation therapy for macroscopic soft tissue sarcomas in 16 dogs

Jessica Lawrence, Lisa Forrest, William Adams, David Vail, Douglas Thamm

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


A retrospective study of 16 dogs with macroscopic soft tissue sarcomas was performed to evaluate response to a four-fraction radiotherapy protocol (prescribed dose of 32 Gy). Radiation was well tolerated with minimal side effects. The overall response rate was 50%, with seven partial responses and one complete response. The median time to progression was 155 days, and the median survival time was 309 days. Coarsely fractionated radiation therapy may be a reasonable palliative option for dogs with unresectable soft tissue sarcomas, although the response is relatively short-lived.

Original languageEnglish (US)
Pages (from-to)100-108
Number of pages9
JournalJournal of the American Animal Hospital Association
Issue number3
StatePublished - 2008


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