Four-color map representation of DNA or RNA sequences and their numerical characterization

Milan Randić, Nella Lerš, Dejan Plavšić, Subhash C. Basak, Alexandru T. Balaban

Research output: Contribution to journalArticlepeer-review

60 Scopus citations


We put forward a novel 2-D graphical representation of DNA or RNA sequences based on a four-color map. The novel representation is rather compact and it not only enables one to carry out a visual inspection of similarity/ dissimilarity between DNA sequences, but also leads to their numerical characterization. The approach is illustrated with the coding sequence of the exon 1 of the human β-globin gene.

Original languageEnglish (US)
Pages (from-to)205-208
Number of pages4
JournalChemical Physics Letters
Issue number1-3
StatePublished - May 17 2005

Bibliographical note

Funding Information:
This work was supported in part by the Ministry of Science, Education and Sports of the Republic of Croatia and Croatian–Slovenian project ‘Application of Discrete Mathematics in Chemistry and Biology’.

Copyright 2008 Elsevier B.V., All rights reserved.


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