Focused Ultrasound Help Realize High Spatiotemporal Brain Imaging?-A Concept on Acousto-Electrophysiological Neuroimaging

Bin He

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

We present a concept for integrating focused ultrasound (FUS) with electrophysiological neuroimaging, in order to achieve high spatiotemporal resolution brain imaging. This approach, which we are tentatively calling acousto-electrophysiological neuroimaging, leverages on the spatial focality and noninvasiveness of FUS and may potentially lead to a noninvasive human brain imaging modality with high resolution in both space and time domains. By the use of modulated FUS, spatial selectivity can be accomplished for high-resolution electrophysiological neuroimaging. Frequency shifting in resulting magnetic signals (using modulated FUS) may potentially open the door for a room temperature magnetoencephalography device.

Original languageEnglish (US)
Article number7676270
Pages (from-to)2654-2656
Number of pages3
JournalIEEE Transactions on Biomedical Engineering
Volume63
Issue number12
DOIs
StatePublished - Dec 2016

Bibliographical note

Funding Information:
This work was supported in part by the National Science Foundation under Grant CBET-1450956, by the National Institutes of Health under Grant NS096761, Grant EB021027, Grant AT009263, Grant EY023101, and Grant HL117664.

Keywords

  • Electroencephalography (EEG)
  • Ultrasound
  • electrophysiological neuroimaging
  • magnetoencephalography (MEG)
  • source imaging
  • source localization

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