Conjugation of a fluorescent saccharide sensor to poly(allylamine) produces a sensing compound with selectivity for ribonucleoside 5'-triphosphate. An association constant (log K(a)) of 5.6 was determined for uridine 5'-triphosphate in pH 7.3 phosphate solution (15 mM, 298 K), whereas log K(a) was less than 2 for uridine, uridine 5'-monophosphate, and uridine 5'-diphosphate.
Bibliographical noteFunding Information:
This work was supported by a Bayer Postdoctoral Fellowship and the National Science Foundation (USA).
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