Flow Cytometry to Assess Cerebrospinal Fluid Fungal Burden in Cryptococcal Meningitis

James E. Scriven, Lisa M. Graham, Charlotte Schutz, Thomas J. Scriba, Robert J. Wilkinson, David R. Boulware, Graeme Meintjes, David G. Lalloo, Britta C. Urban

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Fungal burden in the cerebrospinal fluid is an important determinant of mortality in cryptococcal meningitis, but its use in aiding clinical decision making is hampered by the time involved to perform quantitative cultures. Here, we demonstrate the potential of flow cytometry as a novel and rapid technique to address this issue.

Original languageEnglish (US)
Pages (from-to)802-804
Number of pages3
JournalJournal of clinical microbiology
Volume54
Issue number3
DOIs
StatePublished - Mar 2016

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    Scriven, J. E., Graham, L. M., Schutz, C., Scriba, T. J., Wilkinson, R. J., Boulware, D. R., Meintjes, G., Lalloo, D. G., & Urban, B. C. (2016). Flow Cytometry to Assess Cerebrospinal Fluid Fungal Burden in Cryptococcal Meningitis. Journal of clinical microbiology, 54(3), 802-804. https://doi.org/10.1128/JCM.03002-15