Abstract
Substance P reduces water intake in a dose-dependent manner. In this report we show that the antidipsogenic effect of substance P is markedly reduced when sucrose (2%), saccharine (0.2%) or quinine (0.1%) are added to the water. Addition of saline (0.8%) has no effect on the antidipsogenic effect of substance P. These findings indicate that flavour modulates the antidipsogenic effect of parenterally administered substance P.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 334-338 |
| Number of pages | 5 |
| Journal | Brain Research |
| Volume | 226 |
| Issue number | 1-2 |
| DOIs | |
| State | Published - Dec 7 1981 |
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Keywords
- antidipsogenic
- drinking
- flavor
- fluid ingestion
- substance P
Cite this
Flavour modulates the antidipsogenic effect of substance P. / Morley, John E.; Levine, Allen S; Murray, Samuel S.
In: Brain Research, Vol. 226, No. 1-2, 07.12.1981, p. 334-338.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Flavour modulates the antidipsogenic effect of substance P
AU - Morley, John E.
AU - Levine, Allen S
AU - Murray, Samuel S.
PY - 1981/12/7
Y1 - 1981/12/7
N2 - Substance P reduces water intake in a dose-dependent manner. In this report we show that the antidipsogenic effect of substance P is markedly reduced when sucrose (2%), saccharine (0.2%) or quinine (0.1%) are added to the water. Addition of saline (0.8%) has no effect on the antidipsogenic effect of substance P. These findings indicate that flavour modulates the antidipsogenic effect of parenterally administered substance P.
AB - Substance P reduces water intake in a dose-dependent manner. In this report we show that the antidipsogenic effect of substance P is markedly reduced when sucrose (2%), saccharine (0.2%) or quinine (0.1%) are added to the water. Addition of saline (0.8%) has no effect on the antidipsogenic effect of substance P. These findings indicate that flavour modulates the antidipsogenic effect of parenterally administered substance P.
KW - antidipsogenic
KW - drinking
KW - flavor
KW - fluid ingestion
KW - substance P
UR - http://www.scopus.com/inward/record.url?scp=0019786833&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0019786833&partnerID=8YFLogxK
U2 - 10.1016/0006-8993(81)91108-2
DO - 10.1016/0006-8993(81)91108-2
M3 - Article
C2 - 6170391
AN - SCOPUS:0019786833
VL - 226
SP - 334
EP - 338
JO - Brain Research
JF - Brain Research
SN - 0006-8993
IS - 1-2
ER -