Five-year clinical evaluation of a universal adhesive: A randomized double-blind trial

Thalita de Paris Matos, Jorge Perdigão, Eloisa de Paula, Fabiana Coppla, Viviane Hass, Rafael F. Scheffer, Alessandra Reis, Alessandro D. Loguercio

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69 Scopus citations


OBJECTIVE: To evaluate the five-year clinical performance of Scotchbond Universal Adhesive (SU; 3M Oral Care, St. Paul, MN, USA) in non-carious cervical lesions (NCCLs) using two evaluation criteria.

METHODS: Thirty-nine patients participated in this study. Two hundred restorations were assigned to four groups: SU-ERm: etch-and-rinse + moist dentin; SU-ERd: etch-and-rinse + dry dentin; SU-Set: selective enamel etching; and SU-SE: self-etch. A nanofilled composite resin was placed incrementally. The restorations were evaluated at baseline and after 5 years using both the World Dental Federation (FDI) and the United States Public Health Service (USPHS) criteria. The survival rates (retention/fractures) were calculated with the Kaplan-Meier and the log-rank test. For the secondary outcomes, Friedman repeated measures analysis of variance by rank was applied (α = 0.05).

RESULTS: After 5 years the recall rate was 86%. The retention/fracture rates were 93% for Erm and ERd, 88.4% for SEet and 81.4% for SE. A significant difference was observed for SE vs. ERd and SE vs. ERm (p = 0.01). Also, marginal discoloration and adaptation showed significant differences with ERm and ERd resulting in fewer marginal discrepancies than SE (p < 0.05).

SIGNIFICANCE: After 5 years, the clinical behavior of the universal adhesive in the etch-and-rinse strategy was better when compared to the self-etch strategy. The use of selective enamel etching is highly recommended for the self-etch strategy. The FDI and USPHS evaluation criteria showed similar results after 5 years.

Original languageEnglish (US)
Pages (from-to)1474-1485
Number of pages12
JournalDental Materials
Issue number11
Early online dateSep 12 2020
StatePublished - Nov 2020

Bibliographical note

Publisher Copyright:
© 2020 The Academy of Dental Materials


  • Etch-and-rinse
  • Randomized clinical trial
  • Selective enamel etching
  • Self-etch
  • Universal adhesives


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