Finding better protein engineering strategies

Romas J. Kazlauskas, Uwe T. Bornscheuer

Research output: Contribution to journalComment/debatepeer-review

148 Scopus citations

Abstract

Protein improvement strategies today involve widely varying combinations of rational design with random mutagenesis and screening. To make further progress-defined as making subsequent protein engineering problems easier to solve-protein engineers must critically compare these strategies and eliminate less effective ones.

Original languageEnglish (US)
Pages (from-to)526-529
Number of pages4
JournalNature Chemical Biology
Volume5
Issue number8
DOIs
StatePublished - Aug 2009

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