Field-directed diffusion of charged lipids in supported membranes for spatially addressed microarrays

Yong Sang Ryu, Sang Wook Lee, Byoungho Lee, Sin Doo Lee

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


We demonstrated the field-directed diffusion of charged phospholipids in supported bilayer membranes into distributed partitions in a diffusion cell. The balance between the field-induced drift and the thermal Brownian motion generates the concentration gradient of the charged lipids from partition to partition under an external electric field applied longitudinal to the partition walls. The concentration gradient across the partitions was found to primarily depend on the pore width and the distance between the pore and the partition wall. Our field-directed diffusion approach provides a powerful tool for constructing various spatially addressed membrane arrays.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalMolecular crystals and liquid crystals
StatePublished - Jul 19 2012

Bibliographical note

Funding Information:
This work was supported by the National Research Foundation and the Ministry of Education, Science and Technology of Korea through the Creative Research Initiatives Program (Active Plasmonics Application Systems).


  • Charged lipids
  • field-directed diffusion
  • lipid composition
  • spatially addressed
  • supported membrane


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