The effect of plasmin and the potential role of fibrin degradation products in upgregulating collagen synthesis was investigated. Fibrin has been identified as a strong candidate for use in tissue engineering applications. It was observed that fibrin dramatically incerases collagen synthesis by entrapped cells stimulated by the appropriate combination of exogenous growth factors.
|Original language||English (US)|
|Number of pages||2|
|Journal||American Society of Mechanical Engineers, Bioengineering Division (Publication) BED|
|State||Published - Dec 1 2001|