@article{e0b7c5e3e8f84ba6a6ea77712b94198e,
title = "Fetal brain lesions after subcutaneous inoculation of Zika virus in a pregnant nonhuman primate",
abstract = "We describe the development of fetal brain lesions after Zika virus (ZIKV) inoculation in a pregnant pigtail macaque. Periventricular lesions developed within 10 d and evolved asymmetrically in the occipital-parietal lobes. Fetal autopsy revealed ZIKV in the brain and significant cerebral white matter hypoplasia, periventricular white matter gliosis, and axonal and ependymal injury. Our observation of ZIKV-associated fetal brain lesions in a nonhuman primate provides a model for therapeutic evaluation.",
author = "{Adams Waldorf}, {Kristina M.} and Stencel-Baerenwald, {Jennifer E.} and Kapur, {Raj P.} and Colin Studholme and Erica Boldenow and Jay Vornhagen and Audrey Baldessari and Dighe, {Manjiri K.} and Jeff Thiel and Sean Merillat and Blair Armistead and Jennifer Tisoncik-Go and Green, {Richard R.} and Davis, {Michael A.} and Dewey, {Elyse C.} and Fairgrieve, {Marian R.} and Gatenby, {J. Christopher} and Todd Richards and Garden, {Gwenn A.} and Diamond, {Michael S.} and Juul, {Sandra E.} and Grant, {Richard F.} and Larene Kuller and Shaw, {Dennis W.W.} and Jason Ogle and Gough, {G. Michael} and Wonsok Lee and Chris English and Hevner, {Robert F.} and Dobyns, {William B.} and Michael Gale and Lakshmi Rajagopal",
note = "Publisher Copyright: {\textcopyright} 2016 Nature America, Inc., part of Springer Nature. All rights reserved.",
year = "2016",
month = nov,
day = "1",
doi = "10.1038/nm.4193",
language = "English (US)",
volume = "22",
pages = "1256--1259",
journal = "Nature Medicine",
issn = "1078-8956",
publisher = "Nature Publishing Group",
number = "11",
}