Feedback mechanisms regulate Ets variant 2 (Etv2) gene expression and hematoendothelial lineages

Naoko Koyano-Nakagawa, Xiaozhong Shi, Tara L. Rasmussen, Satyabrata Das, Camille A. Walter, Daniel J. Garry

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

Background: Although Etv2 is an essential transcriptional regulator during embryogenesis, the transcriptional regulation of Etv2 gene expression is not well understood. Results: Multiple signaling cascades were defined as regulators of Etv2 gene expression. Conclusion: These studies define upstream and downstream networks to regulate Etv2 gene expression. Significance: This is the first report to comprehensively characterize the transcriptional regulation of Etv2 gene expression.

Original languageEnglish (US)
Pages (from-to)28107-28119
Number of pages13
JournalJournal of Biological Chemistry
Volume290
Issue number47
DOIs
StatePublished - Nov 20 2015

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