Background: Although Etv2 is an essential transcriptional regulator during embryogenesis, the transcriptional regulation of Etv2 gene expression is not well understood. Results: Multiple signaling cascades were defined as regulators of Etv2 gene expression. Conclusion: These studies define upstream and downstream networks to regulate Etv2 gene expression. Significance: This is the first report to comprehensively characterize the transcriptional regulation of Etv2 gene expression.
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© 2015 by The American Society for Biochemistry and Molecular Biology, Inc. Published in the U.S.A.