Feasibility of Transcranial Motor Evoked Potentials and Electromyography during MRI-Guided Laser Interstitial Thermal Therapy for Glioblastoma

Mayur Sharma, Victoria A. Scott, Tyler Ball, Joshua R. Castle, Joseph Neimat, Brian J. Williams

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Background: Intraoperative neuromonitoring (IONM) is routinely used during neurosurgical procedures. Magnetic resonance imaging (MRI)-guided laser interstitial thermal therapy (LITT) is increasingly being used in patients with various brain lesions. Use of IONM (transcranial motor evoked potential [TcMEP] and electromyography [EMG]) during LITT of a brain lesion has not been described previously. Methods: In this report, we describe a 70-year-old man who presented with motor weakness in whom imaging revealed a left thalamic lesion. Due to the difficulty in accessing the lesion and proximity to the motor tracts, patient was offered MRI-guided LITT using TcMEP and EMG. Results: The patient underwent satisfactory ablation of the lesion with successful recording of the TcMEP and EMG. Technical nuances related to the set-up and procedure is discussed in this report. No procedure-related complications were encountered. Conclusions: We describe the first report of safety and feasibility of TcMEP and EMG during MRI-guided LITT for left thalamic glioblasatoma. This report paves the way for further prospective investigations regarding the utility of this technique for eloquent brain tumors.

Original languageEnglish (US)
Pages (from-to)108-113
Number of pages6
JournalWorld neurosurgery
Volume171
DOIs
StatePublished - Mar 2023

Bibliographical note

Publisher Copyright:
© 2023

Keywords

  • Feasibility
  • Glioblastoma
  • LITT
  • Transcranial motor evoked potentials

PubMed: MeSH publication types

  • Case Reports
  • Journal Article

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