Fbw7 isoform interaction contributes to cyclin E proteolysis

Biochemistry, Genetics and Molecular Biology

• Isoform 100%
• Cyclin E 100%
• Proteolysis 100%
• F-Box Protein 60%
• N-Terminus 60%
• Ubiquitin 60%
• Tumor Suppressor Protein 40%
• Skp1 40%
• Protein Degradation 20%
• Exon 20%
• Proto Oncogene 20%
• Cell Cycle 20%
• Cell Proliferation 20%
• Sequence Motif 20%
• Specificity Factor 20%
• Carcinogenesis 20%
• Proteasome 20%
• Cell Growth 20%
• Ubiquitin Ligase 20%

Keyphrases

• Cyclin E 100%
• Proteolysis 100%
• FBW7 100%
• F-box Protein 27%
• D Domain 27%
• Splice Variant 18%
• Ubiquitin 18%
• Terminal Region 18%
• Tumor Protein p53 (TP53) 18%
• SKP1 18%
• Cell Growth 9%
• Cell Proliferation 9%
• Functional Significance 9%
• Protein Turnover 9%
• Oncogene 9%
• Tumorigenesis 9%
• Ubiquitin Ligase 9%
• Homodimeric 9%
• Ubiquitin-proteasome System 9%
• Substrate Binding 9%
• Sequence Motif 9%
• E Protein 9%
• Cell Cycle Regulators 9%
• Reduced Rate 9%
• Orthologues 9%
• Oncogene Products 9%
• Substrate Turnover 9%
• Heteromeric Complexes 9%
• Specificity Factor 9%
• CUL1 9%
• First Exons 9%