Recrudescence of latent and dormant viruses may lead to overwhelming viremia in immunosuppressed hosts. In immunocompromised hosts, Simian virus 40 (SV40) reactivation is known to cause nephritis and demyelinating central nervous system disease. Here, we report SV40 viremia leading to fatal interstitial pneumonia in an immunosuppressed host following renal allotransplantation.
Bibliographical noteFunding Information:
This study was funded by NIH grant #U19-AI051731 (ADK).
© 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
- opportunistic infection
- renal transplant
- rhesus macaque
- viral reactivation