Abstract
A 35-year-old man had symptomatic hyperammonemia and normal liver function after repeat kidney transplantation. He presented with gastrointestinal symptoms, which quickly progressed to altered mental status. Therapy was instituted to clear the ammonia, but the ammonia level continued to rise. Eventually, the patient became unresponsive, and an emergent computed tomographic scan showed cerebral herniation. Urine acids and serum organic acids were not diagnostic of any urea cycle disorder. Histology did not reveal a clear etiology for the hyperammonemia.
Original language | English (US) |
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Pages (from-to) | 164-167 |
Number of pages | 4 |
Journal | Journal of Clinical Anesthesia |
Volume | 27 |
Issue number | 2 |
DOIs | |
State | Published - Mar 1 2015 |
Bibliographical note
Publisher Copyright:© 2014 Elsevier Inc. All rights reserved.
Keywords
- Acid-base balance
- Critical care issues
- Drugs used in anesthesia and critical care medicine
- Fluid management/replacement therapy
- Kidney
- Transplantation