Fat-containing hypermetabolic masses on FDG PET/CT: A spectrum of benign and malignant conditions

Chara Rydzak, Anil Chauhan, Narainder Gupta, Hubert H. Chuang, Eric M. Rohren, Priya R. Bhosale

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Objective. This article focuses on identifying the imaging appearances of hypermetabolic fatty masses and masslike lesions on PET/CT and understanding the diagnostic challenges radiologists may face while interpreting fndings of these lesions on PET/CT. This article provides an approach to aid in the diagnosis of these lesions and the appropriate management of patients. CONCLUSION. Both malignant and benign fat-containing masses and masslike lesions can show hypermetabolic activity on PET/CT. Although the differential diagnosis is broad, clinical history, anatomic location, and knowledge of anatomic variants and imaging features can help radiologists avoid misinterpretation of benign fatty lesions as malignancy.

Original languageEnglish (US)
Pages (from-to)1095-1104
Number of pages10
JournalAmerican Journal of Roentgenology
Issue number5
StatePublished - Nov 2016
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2016 American Roentgen Ray Society.


  • Benign
  • Fatty Mass
  • Hypermetabolic
  • Malignant
  • PET/CT


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