Despite the advantages of compensation for resonance offset and B 1 inhomogeneity, adiabatic pulses are not yet in general use in high-resolution NMR, often because of the conception that these pulses require longer time or increased power to perform. We show that adiabatic pulses with tangential frequency sweeps and other frequency-modulation functions can be optimized to accomplish 13 C and 1 H broadband inversion using pulse lengths of 192 and 64 μs, respectively, at B 1 strengths available with modern high-resolution probes.
Bibliographical noteFunding Information:
This research was supported by NIH Grants RR11115 (PvZ) and RR08079 (MG), and, in part, via a subcontract of NIH STTR Grant GM55441 to Adiabatics, Inc., of which M.G. and P.v.Z. are officers. The terms of this agreement have been reviewed and approved by the Johns Hopkins University in accordance with its conflict of interest policies.
Copyright 2019 Elsevier B.V., All rights reserved.
- Adiabatic pulses
- Fast broadband inversion
- Tangential frequency sweep