Family History, Body-Fat Distribution, and the Risk of Breast Cancer

E. Taioli, E. L. Wynder, T. A. Sellers, J. D. Potter, A. R. Folsom

Research output: Contribution to journalLetterpeer-review

6 Scopus citations

Abstract

To the Editor: Sellers et al. (May 14 issue)1 suggest an interaction between a family history of breast cancer and anthropometric factors in postmenopausal women. A genetic component of body mass has been observed not only among overweight subjects but also among thin persons.2 Since thinness is considered a risk factor for breast cancer in premenopausal women,3 and a family history of breast cancer is a strong risk factor in premenopausal women, the same interaction should be present in premenopausal women as well. We analyzed data from our case–control study, in which 617 patients with newly diagnosed breast cancer and…

Original languageEnglish (US)
Pages (from-to)958-959
Number of pages2
JournalNew England Journal of Medicine
Volume327
Issue number13
DOIs
StatePublished - Sep 24 1992

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