Family history and brain morphology in schizophrenia: An MRI study

Steven B. Schwarzkopf; Henry A. Nasrallah; Stephen C. Olson; Bernhard Bogerts; Judy A. McLaughlin; Tanmoy Mitra

doi:10.1016/0925-4927(91)90028-O

Family history and brain morphology in schizophrenia: An MRI study

Steven B. Schwarzkopf, Henry A. Nasrallah, Stephen C. Olson, Bernhard Bogerts, Judy A. McLaughlin, Tanmoy Mitra

Psychiatry & Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

34 Scopus citations

Abstract

This study examined neuroanatomical differences between male schizophrenic patients with a family history of psychosis (n = 16) and those without such a history (n = 15). Intracranial area, cerebral area, ventricular size, and cortical atrophy were assessed using magnetic resonance imaging (MRI). Third ventricular enlargement was more prevalent in patients than controls (n = 15). Familial and nonfamilial patients differed significantly. Reduced cranial and cerebral areas without ventricular enlargement characterized familial patients, whereas nonfamilial patients showed marked lateral ventricular enlargement without a reduction in cranial/cerebral size.

Original language	English (US)
Pages (from-to)	49-60
Number of pages	12
Journal	Psychiatry Research: Neuroimaging
Volume	40
Issue number	1
DOIs	https://doi.org/10.1016/0925-4927(91)90028-O
State	Published - May 1991

Keywords

Schizophrenia
family history
magnetic resonance imaging

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Family history and brain morphology in schizophrenia: An MRI study

Abstract

Keywords

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