TY - JOUR
T1 - Failure of Vaccination with Haemophilus influenzae Vaccine
AU - Pritikin, Ronald
AU - Daum, Robert S.
AU - Osterholm, Michael T.
AU - Granoff, Dan M.
PY - 1987/7/9
Y1 - 1987/7/9
N2 - To the Editor: The article by Granoff et al. (Dec. 18 issue)1 raises several points of concern. Although the extent of the network of physicians reporting to the investigators is uncertain, the accepted incidence of Haemophilus influenzae disease in the age bracket of 24 to 48 months is 1:2000.2 With a “vaccine failure” rate of 10 percent, the incidence among those vaccinated becomes 1:20,000. Forty-three cases in the 24- to 48-month age group at immunization would require a cohort of almost 1 million children, or about one seventh of all the children in the country in that age bracket. If…
AB - To the Editor: The article by Granoff et al. (Dec. 18 issue)1 raises several points of concern. Although the extent of the network of physicians reporting to the investigators is uncertain, the accepted incidence of Haemophilus influenzae disease in the age bracket of 24 to 48 months is 1:2000.2 With a “vaccine failure” rate of 10 percent, the incidence among those vaccinated becomes 1:20,000. Forty-three cases in the 24- to 48-month age group at immunization would require a cohort of almost 1 million children, or about one seventh of all the children in the country in that age bracket. If…
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U2 - 10.1056/NEJM198707093170212
DO - 10.1056/NEJM198707093170212
M3 - Letter
C2 - 3495734
AN - SCOPUS:0023649060
SN - 0028-4793
VL - 317
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 2
ER -
