Abstract
The effect of ascorbic acid on the growth of 7,12-dimethylbenzanthracene (DMBA)-induced mammary tumor and on growth of R3230AC and MT/W9-B transplantable rat mammary tumors was investigated. High doses of ascorbic acid averaging about 540 mg/day/rat administered orally in drinking water had no effect on the growth of both R3230A and MT/W9a-B transplantable mammary tumors. Furthermore, vitamin C was unable to postpone tumor induction, reduce tumor incidence or prolong survival time of rats treated with DMBA.
Original language | English (US) |
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Pages (from-to) | 67-73 |
Number of pages | 7 |
Journal | Cancer Letters |
Volume | 17 |
Issue number | 1 |
DOIs | |
State | Published - Oct 1982 |