Factors associated with genetic testing in a cohort of breast cancer survivors

Anne H Blaes; Patricia I. Jewett; Kathleen McKay; Danielle Riley; Ismail Jatoi; Amy Trentham-Dietz; Elizabeth Chrischilles; Jennifer R. Klemp

doi:10.1111/tbj.13440

Factors associated with genetic testing in a cohort of breast cancer survivors

Anne H Blaes, Patricia I. Jewett, Kathleen McKay, Danielle Riley, Ismail Jatoi, Amy Trentham-Dietz, Elizabeth Chrischilles, Jennifer R. Klemp

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

We examined factors associated with self-reported use of genetic testing among breast cancer survivors based on a 2015 cross-sectional survey at eight Midwestern sites. Genetic testing was reported in 39% of our 1235 study participants, with higher utilization among those aged <50 and with a triple-negative cancer. Bilateral mastectomy, having relatives with breast cancer, and younger age were associated with increased genetic testing use. Increasing income, in interaction with age, was associated with use of genetic testing among younger but not older patients. Rural residency emerged as a possible barrier for genetic testing among women with triple-negative cancer.

Original language	English (US)
Pages (from-to)	1241-1244
Number of pages	4
Journal	Breast Journal
Volume	25
Issue number	6
DOIs	https://doi.org/10.1111/tbj.13440
State	Published - Nov 1 2019

Bibliographical note

Funding Information:
This study was supported by the Patient-Centered Outcomes Research Institute (PCORI) contract CDRN-1306-04631. We would like to thank Jody Rock, our patient advocate.

Publisher Copyright:
© 2019 Wiley Periodicals, Inc.

Keywords

breast cancer
cancer genetic testing
pathogenic germline variant

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/tbj.13440

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title = "Factors associated with genetic testing in a cohort of breast cancer survivors",

abstract = "We examined factors associated with self-reported use of genetic testing among breast cancer survivors based on a 2015 cross-sectional survey at eight Midwestern sites. Genetic testing was reported in 39% of our 1235 study participants, with higher utilization among those aged <50 and with a triple-negative cancer. Bilateral mastectomy, having relatives with breast cancer, and younger age were associated with increased genetic testing use. Increasing income, in interaction with age, was associated with use of genetic testing among younger but not older patients. Rural residency emerged as a possible barrier for genetic testing among women with triple-negative cancer.",

keywords = "breast cancer, cancer genetic testing, pathogenic germline variant",

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note = "Funding Information: This study was supported by the Patient-Centered Outcomes Research Institute (PCORI) contract CDRN-1306-04631. We would like to thank Jody Rock, our patient advocate. Publisher Copyright: {\textcopyright} 2019 Wiley Periodicals, Inc.",

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AU - Riley, Danielle

AU - Jatoi, Ismail

AU - Trentham-Dietz, Amy

AU - Chrischilles, Elizabeth

AU - Klemp, Jennifer R.

N1 - Funding Information: This study was supported by the Patient-Centered Outcomes Research Institute (PCORI) contract CDRN-1306-04631. We would like to thank Jody Rock, our patient advocate. Publisher Copyright: © 2019 Wiley Periodicals, Inc.

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N2 - We examined factors associated with self-reported use of genetic testing among breast cancer survivors based on a 2015 cross-sectional survey at eight Midwestern sites. Genetic testing was reported in 39% of our 1235 study participants, with higher utilization among those aged <50 and with a triple-negative cancer. Bilateral mastectomy, having relatives with breast cancer, and younger age were associated with increased genetic testing use. Increasing income, in interaction with age, was associated with use of genetic testing among younger but not older patients. Rural residency emerged as a possible barrier for genetic testing among women with triple-negative cancer.

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KW - cancer genetic testing

KW - pathogenic germline variant

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Factors associated with genetic testing in a cohort of breast cancer survivors

Abstract

Bibliographical note

Keywords

UN SDGs

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