TY - JOUR
T1 - Factor V Leiden
T2 - How great is the risk of venous thromboembolism?
AU - Shaheen, Khaldoon
AU - Chadi Alraies, M.
AU - Alraiyes, Abdul Hamid
AU - Christie, Richard
PY - 2012/4
Y1 - 2012/4
N2 - The factor V Leiden mutation, the most common inherited cause of thrombophilia, causes a mild hypercoagulable state. We describe a 29-year-old man, heterozygous for factor V Leiden, who developed extensive pulmonary emboli with concomitant bilateral deep venous thrombosis, likely provoked by prolonged immobility during a car trip. We then review the diagnosis, therapy, screening, and prognosis of venous thromboembolism related to factor V Leiden.
AB - The factor V Leiden mutation, the most common inherited cause of thrombophilia, causes a mild hypercoagulable state. We describe a 29-year-old man, heterozygous for factor V Leiden, who developed extensive pulmonary emboli with concomitant bilateral deep venous thrombosis, likely provoked by prolonged immobility during a car trip. We then review the diagnosis, therapy, screening, and prognosis of venous thromboembolism related to factor V Leiden.
UR - http://www.scopus.com/inward/record.url?scp=84862984613&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84862984613&partnerID=8YFLogxK
U2 - 10.3949/ccjm.79a.11072
DO - 10.3949/ccjm.79a.11072
M3 - Review article
C2 - 22473726
AN - SCOPUS:84862984613
SN - 0891-1150
VL - 79
SP - 265
EP - 272
JO - Cleveland Clinic journal of medicine
JF - Cleveland Clinic journal of medicine
IS - 4
ER -