Facile synthesis of Graphene Oxide/Double-stranded DNA composite liquid crystals and Hydrogels

Rajendra Kurapati, U. Venkateswara Reddy, Ashok M. Raichur, N. Suryaprakash

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Investigation of the interactions between graphene oxide (GO) and biomolecules is very crucial for the development of biomedical applications based on GO. This study reports the first observation of the spontaneous formation of self-assembled liquid crystals and three-dimensional hydrogels of graphene oxide with double-stranded DNA by simple mixing in an aqueous buffer media without unwinding double-stranded DNA to single-stranded DNA. The GO/dsDNA hydrogels have shown controlled porosity by changing the concentration of the components. The strong binding between dsDNA and graphene is proved by Raman spectroscopy.

Original languageEnglish (US)
Pages (from-to)325-330
Number of pages6
JournalJournal of Chemical Sciences
Issue number3
StatePublished - Mar 1 2016
Externally publishedYes

Bibliographical note

Funding Information:
Our sincere thanks to Dr. Ravula Thirupathi (University of Michigan) for his kind help in the schematic diagrams as well as in the discussion part. We also acknowledge Council of Scientific and Industrial Research (CSIR), India for the financial support by providing research fellowships.

Publisher Copyright:
© 2016 Indian Academy of Sciences.


  • DNA
  • Graphene oxide
  • hydrogels
  • liquid crystals
  • self-assembly


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