Extubation readiness in preterm infants: Evaluating the role of monitoring intermittent hypoxemia

Elie G. Abu Jawdeh; Amrita Pant; Aayush Gabrani; M. Douglas Cunningham; Thomas M. Raffay; Philip M. Westgate

doi:10.3390/children8030237

Extubation readiness in preterm infants: Evaluating the role of monitoring intermittent hypoxemia

Elie G. Abu Jawdeh, Amrita Pant, Aayush Gabrani, M. Douglas Cunningham, Thomas M. Raffay, Philip M. Westgate

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Preterm infants with respiratory distress may require mechanical ventilation which is associated with increased pulmonary morbidities. Prompt and successful extubation to noninvasive support is a pressing goal. In this communication, we show original data that increased recurring intermittent hypoxemia (IH, oxygen saturation <80%) may be associated with extubation failure at 72 h in a cohort of neonates <30 weeks gestational age. Current-generation bedside high-resolution pulse oximeters provide saturation profiles that may be of use in identifying extubation readiness and failure. A larger prospective study that utilizes intermittent hypoxemia as an adjunct predictor for extubation readiness is warranted.

Original language	English (US)
Article number	237
Journal	Children
Volume	8
Issue number	3
DOIs	https://doi.org/10.3390/children8030237
State	Published - Mar 2021
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.

Keywords

Extubation
Intermittent hypoxemia
Intubation
Preterm
Respiratory distress

Publisher link

10.3390/children8030237

Find It

Find It at U of M Libraries

Cite this

@article{c41d7c6f9af643adb4f9126a6e2aeb8e,

title = "Extubation readiness in preterm infants: Evaluating the role of monitoring intermittent hypoxemia",

abstract = "Preterm infants with respiratory distress may require mechanical ventilation which is associated with increased pulmonary morbidities. Prompt and successful extubation to noninvasive support is a pressing goal. In this communication, we show original data that increased recurring intermittent hypoxemia (IH, oxygen saturation <80%) may be associated with extubation failure at 72 h in a cohort of neonates <30 weeks gestational age. Current-generation bedside high-resolution pulse oximeters provide saturation profiles that may be of use in identifying extubation readiness and failure. A larger prospective study that utilizes intermittent hypoxemia as an adjunct predictor for extubation readiness is warranted.",

keywords = "Extubation, Intermittent hypoxemia, Intubation, Preterm, Respiratory distress",

author = "{Abu Jawdeh}, {Elie G.} and Amrita Pant and Aayush Gabrani and Cunningham, {M. Douglas} and Raffay, {Thomas M.} and Westgate, {Philip M.}",

note = "Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2021",

month = mar,

doi = "10.3390/children8030237",

language = "English (US)",

volume = "8",

journal = "Children",

issn = "2227-9067",

publisher = "MDPI AG",

number = "3",

}

TY - JOUR

T1 - Extubation readiness in preterm infants

T2 - Evaluating the role of monitoring intermittent hypoxemia

AU - Abu Jawdeh, Elie G.

AU - Pant, Amrita

AU - Gabrani, Aayush

AU - Cunningham, M. Douglas

AU - Raffay, Thomas M.

AU - Westgate, Philip M.

PY - 2021/3

Y1 - 2021/3

N2 - Preterm infants with respiratory distress may require mechanical ventilation which is associated with increased pulmonary morbidities. Prompt and successful extubation to noninvasive support is a pressing goal. In this communication, we show original data that increased recurring intermittent hypoxemia (IH, oxygen saturation <80%) may be associated with extubation failure at 72 h in a cohort of neonates <30 weeks gestational age. Current-generation bedside high-resolution pulse oximeters provide saturation profiles that may be of use in identifying extubation readiness and failure. A larger prospective study that utilizes intermittent hypoxemia as an adjunct predictor for extubation readiness is warranted.

AB - Preterm infants with respiratory distress may require mechanical ventilation which is associated with increased pulmonary morbidities. Prompt and successful extubation to noninvasive support is a pressing goal. In this communication, we show original data that increased recurring intermittent hypoxemia (IH, oxygen saturation <80%) may be associated with extubation failure at 72 h in a cohort of neonates <30 weeks gestational age. Current-generation bedside high-resolution pulse oximeters provide saturation profiles that may be of use in identifying extubation readiness and failure. A larger prospective study that utilizes intermittent hypoxemia as an adjunct predictor for extubation readiness is warranted.

KW - Extubation

KW - Intermittent hypoxemia

KW - Intubation

KW - Preterm

KW - Respiratory distress

UR - http://www.scopus.com/inward/record.url?scp=85112453440&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85112453440&partnerID=8YFLogxK

U2 - 10.3390/children8030237

DO - 10.3390/children8030237

M3 - Article

AN - SCOPUS:85112453440

SN - 2227-9067

VL - 8

JO - Children

JF - Children

IS - 3

M1 - 237

ER -

Extubation readiness in preterm infants: Evaluating the role of monitoring intermittent hypoxemia

Abstract

Bibliographical note

Keywords

Publisher link

Find It

Other files and links

Fingerprint

Cite this