Extraintestinal pathogenic Escherichia coli: "The other bad E coli"

James R. Johnson, Thomas A. Russo

Research output: Contribution to journalArticlepeer-review

305 Scopus citations


Extraintestinal pathogenic Escherichia coli (ExPEC), the specialized strains of E coli that cause most extraintestinal E coli infections, represent a major but little-appreciated health threat. Although the reasons for their evolution remain mysterious, by virtue of their numerous virulence traits ExPEC clearly possess a unique ability to cause disease outside the host intestinal tract. Broader appreciation of the existence and importance of ExPEC and better understandings of their distinctive virulence mechanisms, reservoirs, and transmission pathways may lead to effective preventive interventions against the morbid and costly infections ExPEC cause.

Original languageEnglish (US)
Pages (from-to)155-162
Number of pages8
JournalJournal of Laboratory and Clinical Medicine
Issue number3
StatePublished - 2002


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