Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome

The Doctors are In, but the Jury is Still Out

Research output: Contribution to journalArticle

Abstract

Despite attempts to optimize outcomes in acute respiratory distress syndrome (ARDS) using mechanical ventilation and medical management, the mortality associated with this syndrome remains very high. The use of extracorporeal membrane oxygenation (ECMO), particularly veno-venous ECMO (VV-ECMO), as a rescue therapy has grown significantly in recent decades. This review outlines the risks and benefits of ECMO for the treatment of ARDS, examines the body of evidence behind this practice, including 4 randomized controlled trials and 2 case-controlled studies, and discusses the remaining questions and directions for future research. Because VV-ECMO is far more frequently used in the treatment of ARDS than veno-arterial ECMO, referral to ECMO in this review will imply VV-ECMO unless specifically stated.

Original languageEnglish (US)
Pages (from-to)39-45
Number of pages7
JournalClinical Pulmonary Medicine
Volume26
Issue number2
DOIs
StatePublished - Mar 1 2019

Fingerprint

Extracorporeal Membrane Oxygenation
Adult Respiratory Distress Syndrome
Artificial Respiration
Therapeutics
Referral and Consultation
Randomized Controlled Trials
Mortality

Keywords

  • acute respiratory distress syndrome
  • ARDS
  • ECMO
  • extracorporeal membrane oxygenation

Cite this

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abstract = "Despite attempts to optimize outcomes in acute respiratory distress syndrome (ARDS) using mechanical ventilation and medical management, the mortality associated with this syndrome remains very high. The use of extracorporeal membrane oxygenation (ECMO), particularly veno-venous ECMO (VV-ECMO), as a rescue therapy has grown significantly in recent decades. This review outlines the risks and benefits of ECMO for the treatment of ARDS, examines the body of evidence behind this practice, including 4 randomized controlled trials and 2 case-controlled studies, and discusses the remaining questions and directions for future research. Because VV-ECMO is far more frequently used in the treatment of ARDS than veno-arterial ECMO, referral to ECMO in this review will imply VV-ECMO unless specifically stated.",
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