Extracorporeal CPR after the INCEPTION trial: No one steps twice into the same river

Tommaso Scquizzato; Demetris Yannopoulos; Jan Bělohlávek; Fabio S. Taccone; Roberto Lorusso; Anna Mara Scandroglio; Giovanni Landoni; Justyna Swol

doi:10.1111/aor.14520

Extracorporeal CPR after the INCEPTION trial: No one steps twice into the same river

Tommaso Scquizzato, Demetris Yannopoulos, Jan Bělohlávek, Fabio S. Taccone, Roberto Lorusso, Anna Mara Scandroglio, Giovanni Landoni, Justyna Swol

Medicine - Cardiology Division

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The use of veno-arterial extracorporeal membrane oxygenation as extracorporeal cardiopulmonary resuscitation in patients suffering out-of-hospital cardiac arrest, largely increased in the last decade despite evidence supporting this practice being limited to non-randomized studies. However, between 2020 and 2023, four randomized studies were published comparing extracorporeal cardiopulmonary resuscitation to conventional cardiopulmonary resuscitation with controversial findings that triggered great debates. In this controversy, we discuss merits and pitfalls, and provide a critical interpretation of the available evidence from randomized trials on the use of extracorporeal cardiopulmonary resuscitation, with a particular focus on the recent multi-center INCEPTION trial.

Original language	English (US)
Pages (from-to)	802-805
Number of pages	4
Journal	Artificial Organs
Volume	47
Issue number	5
DOIs	https://doi.org/10.1111/aor.14520
State	Published - May 2023

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Publisher Copyright:
© 2023 The Authors. Artificial Organs published by International Center for Artificial Organ and Transplantation (ICAOT) and Wiley Periodicals LLC.

Keywords

ECLS
ECMO
ECPR
OHCA
extracorporeal cardiopulmonary resuscitation
extracorporeal life support
extracorporeal membrane oxygenation
out-of-hospital cardiac arrest

PubMed: MeSH publication types

Journal Article

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10.1111/aor.14520

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title = "Extracorporeal CPR after the INCEPTION trial: No one steps twice into the same river",

abstract = "The use of veno-arterial extracorporeal membrane oxygenation as extracorporeal cardiopulmonary resuscitation in patients suffering out-of-hospital cardiac arrest, largely increased in the last decade despite evidence supporting this practice being limited to non-randomized studies. However, between 2020 and 2023, four randomized studies were published comparing extracorporeal cardiopulmonary resuscitation to conventional cardiopulmonary resuscitation with controversial findings that triggered great debates. In this controversy, we discuss merits and pitfalls, and provide a critical interpretation of the available evidence from randomized trials on the use of extracorporeal cardiopulmonary resuscitation, with a particular focus on the recent multi-center INCEPTION trial.",

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author = "Tommaso Scquizzato and Demetris Yannopoulos and Jan B{\v e}lohl{\'a}vek and Taccone, {Fabio S.} and Roberto Lorusso and Scandroglio, {Anna Mara} and Giovanni Landoni and Justyna Swol",

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AU - Scquizzato, Tommaso

AU - Yannopoulos, Demetris

AU - Bělohlávek, Jan

AU - Taccone, Fabio S.

AU - Lorusso, Roberto

AU - Scandroglio, Anna Mara

AU - Landoni, Giovanni

AU - Swol, Justyna

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Extracorporeal CPR after the INCEPTION trial: No one steps twice into the same river

Abstract

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Keywords

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