Extracorporeal cardiopulmonary resuscitation for cardiac arrest

Rajat Kalra; Marinos Kosmopoulos; Tomaz Goslar; Ganesh Raveendran; Jason A. Bartos; Demetris Yannopoulos

doi:10.1097/MCC.0000000000000717

Extracorporeal cardiopulmonary resuscitation for cardiac arrest

Rajat Kalra, Marinos Kosmopoulos, Tomaz Goslar, Ganesh Raveendran, Jason A. Bartos, Demetris Yannopoulos

Medicine - Cardiology Division

Research output: Contribution to journal › Review article › peer-review

12 Scopus citations

Abstract

Purpose of review Extracorporeal cardiopulmonary resuscitation (ECPR) is a contemporary resuscitation approach that employs veno-arterial extracorporeal membrane oxygenation (VA-ECMO). This approach is increasingly used worldwide to mitigate the widespread hemodynamic and multiorgan dysfunction that accompanies cardiac arrest. Recent findings In this review, the physiology of VA-ECMO and ECPR, the role of ECPR in contemporary resuscitation care, the complications associated with ECPR and VA-ECMO usage, and intensive care considerations for this population are discussed. Summary ECPR offers a promising mechanism to mitigate multiorgan injury and allow time for the institution of supportive interventions required to effectively treat cardiac arrest. More prospective data in the context of extensive prehospital and hospital collaboration is needed to promote its successful use.

Original language	English (US)
Pages (from-to)	228-235
Number of pages	8
Journal	Current opinion in critical care
Volume	26
Issue number	3
DOIs	https://doi.org/10.1097/MCC.0000000000000717
State	Published - Jun 1 2020

Bibliographical note

Funding Information:
D.Y. has received NIH funds related to basic and clinical CPR research from the National Heart, Lung, and Blood Institute (award numbers 5U01HL133818-03 and 4R33HL142696-02) and a grant from the Helmsley Philanthropic Trust for the broad community implementation of ECPR and mobile ECPR in the Minneapolis St Paul metropolitan area.

Publisher Copyright:
Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.

Keywords

cardiac arrest
cardiopulmonary resuscitation
extracorporeal cardiopulmonary resuscitation
extracorporeal membrane oxygenation

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10.1097/MCC.0000000000000717

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abstract = "Purpose of review Extracorporeal cardiopulmonary resuscitation (ECPR) is a contemporary resuscitation approach that employs veno-arterial extracorporeal membrane oxygenation (VA-ECMO). This approach is increasingly used worldwide to mitigate the widespread hemodynamic and multiorgan dysfunction that accompanies cardiac arrest. Recent findings In this review, the physiology of VA-ECMO and ECPR, the role of ECPR in contemporary resuscitation care, the complications associated with ECPR and VA-ECMO usage, and intensive care considerations for this population are discussed. Summary ECPR offers a promising mechanism to mitigate multiorgan injury and allow time for the institution of supportive interventions required to effectively treat cardiac arrest. More prospective data in the context of extensive prehospital and hospital collaboration is needed to promote its successful use.",

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note = "Funding Information: D.Y. has received NIH funds related to basic and clinical CPR research from the National Heart, Lung, and Blood Institute (award numbers 5U01HL133818-03 and 4R33HL142696-02) and a grant from the Helmsley Philanthropic Trust for the broad community implementation of ECPR and mobile ECPR in the Minneapolis St Paul metropolitan area. Publisher Copyright: Copyright {\textcopyright} 2020 Wolters Kluwer Health, Inc. All rights reserved.",

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AU - Kalra, Rajat

AU - Kosmopoulos, Marinos

AU - Goslar, Tomaz

AU - Raveendran, Ganesh

AU - Bartos, Jason A.

AU - Yannopoulos, Demetris

N1 - Funding Information: D.Y. has received NIH funds related to basic and clinical CPR research from the National Heart, Lung, and Blood Institute (award numbers 5U01HL133818-03 and 4R33HL142696-02) and a grant from the Helmsley Philanthropic Trust for the broad community implementation of ECPR and mobile ECPR in the Minneapolis St Paul metropolitan area. Publisher Copyright: Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.

PY - 2020/6/1

Y1 - 2020/6/1

N2 - Purpose of review Extracorporeal cardiopulmonary resuscitation (ECPR) is a contemporary resuscitation approach that employs veno-arterial extracorporeal membrane oxygenation (VA-ECMO). This approach is increasingly used worldwide to mitigate the widespread hemodynamic and multiorgan dysfunction that accompanies cardiac arrest. Recent findings In this review, the physiology of VA-ECMO and ECPR, the role of ECPR in contemporary resuscitation care, the complications associated with ECPR and VA-ECMO usage, and intensive care considerations for this population are discussed. Summary ECPR offers a promising mechanism to mitigate multiorgan injury and allow time for the institution of supportive interventions required to effectively treat cardiac arrest. More prospective data in the context of extensive prehospital and hospital collaboration is needed to promote its successful use.

AB - Purpose of review Extracorporeal cardiopulmonary resuscitation (ECPR) is a contemporary resuscitation approach that employs veno-arterial extracorporeal membrane oxygenation (VA-ECMO). This approach is increasingly used worldwide to mitigate the widespread hemodynamic and multiorgan dysfunction that accompanies cardiac arrest. Recent findings In this review, the physiology of VA-ECMO and ECPR, the role of ECPR in contemporary resuscitation care, the complications associated with ECPR and VA-ECMO usage, and intensive care considerations for this population are discussed. Summary ECPR offers a promising mechanism to mitigate multiorgan injury and allow time for the institution of supportive interventions required to effectively treat cardiac arrest. More prospective data in the context of extensive prehospital and hospital collaboration is needed to promote its successful use.

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Extracorporeal cardiopulmonary resuscitation for cardiac arrest

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