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Expression of the platencin biosynthetic gene cluster in heterologous hosts yielding new platencin congeners
Michael J. Smanski
, Jeffrey Casper
, Ryan M. Peterson
, Zhiguo Yu
, Scott R. Rajski
, Ben Shen
Biochemistry, Molecular Biology, and Biophysics (CBS)
Research output
:
Contribution to journal
›
Article
›
peer-review
40
Scopus citations
Overview
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Dive into the research topics of 'Expression of the platencin biosynthetic gene cluster in heterologous hosts yielding new platencin congeners'. Together they form a unique fingerprint.
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Keyphrases
Antibacterial Therapy
7%
Antidiabetic Therapy
7%
Biosynthesis Regulation
7%
Biosynthetic Gene Clusters
100%
Biosynthetic Strategies
7%
Drug Lead
7%
Expression Construct
7%
Fatty Acid Synthase
7%
Heterologous Host
100%
Pathway-specific Regulator
7%
Platencin
100%
Platensimycin
21%
Potent Inhibitor
7%
Promising Drug
7%
Recombinant Strain
7%
S. Platensis
14%
Selective Inhibitor
7%
Streptomyces Host
21%
Streptomyces Lividans
7%
Streptomyces Platensis
7%
Structural Diversity
7%
Biochemistry, Genetics and Molecular Biology
Anabolism
40%
Fatty Acid Synthase
20%
Gene Cluster
100%
Streptomyces
80%
Streptomyces Lividans
20%
Immunology and Microbiology
Fatty Acid
20%
Gene Cluster
100%
Streptomyces
80%
Streptomyces Lividans
20%