Summary: Carter and colleagues propose a systematic analysis of the germline and somatic genome in cancer. They identify interactions that occur between germline and somatic variants. This elucidates the function of the germline genome in the context of cancer risk and development
Bibliographical noteFunding Information:
R.S. Huang has received support from the Avon Foundation research grant, NIH/NIGMS grant K08GM089941, NIH/NCI grant R21 CA139278, NIH/NIGMS grant UO1GM61393, the Circle of Service Foundation Early Career Investigator award, The University of Chicago Support Grant (#P30 CA14599), the Breast Cancer SPORE Career Development Award (CA125183), the National Center for Advancing Translational Sciences of the NIH (UL1RR024999), The University of Chicago CTSA core subsidy grant, and a Conquer Cancer Foundation of ASCO Translational Research Professorship Award In Memory of Merrill J. Egorin, MD (awarded to Dr. M.J. Ratain). P. Geeleher received support from the Chicago Biomedical Consortium grant PDR-020.
© 2017 American Association for Cancer Research.