Exploration of Cascade Cyclizations Terminated by Tandem Aromatic Substitution: Total Synthesis of (+)-Schweinfurthin A

Keyphrases

• Total Synthesis 100%
• Aromatic Substitution 100%
• Cascade Cyclization 100%
• Schweinfurthin 100%
• Antiproliferative Activity 50%
• Epoxides 50%
• Electrophile 50%
• First Total Synthesis 50%
• Protecting Groups 50%
• Number of Groups 50%
• Substitution Reaction 50%
• Regiochemistry 50%
• Ring Closure 50%
• Cascade Process 50%

Chemistry

• Aromatic Substitution 100%
• Antiproliferative 50%
• Substitution Reaction 50%
• Epoxide 50%
• Regiochemistry 50%
• Phenol 50%
• Protecting Groups 50%
• Electrophile 50%