Experimental viral spillover across 25 million year gap in Rodentia reveals limited viral transmission and purifying selection of a picornavirus

Keyphrases

• Viral Transmission 100%
• Cross-species Transmission 100%
• Purifying Selection 100%
• Rodentia 100%
• Picornavirus 100%
• Virus Spillover 100%
• Virus 75%
• Viral Evolution 50%
• Spillover Event 50%
• Natural Transmission 50%
• High-resolution 25%
• Public Health 25%
• Viral 25%
• Natural Variation 25%
• Coronavirus 25%
• Tight 25%
• Health Consequences 25%
• Population Structure 25%
• Deep Sequencing 25%
• Virome 25%
• Next-generation Sequencing 25%
• Host Species 25%
• RNA Sequencing (RNA-seq) 25%
• Physiologically Relevant 25%
• New Animal Model 25%
• New Host 25%
• Viral Populations 25%
• Peromyscus 25%
• Mouse Mus musculus 25%
• Fecal-oral Route 25%
• Pet Store 25%
• Kobuvirus 25%
• Deer Mice 25%
• Intra-host 25%
• Peromyscus Maniculatus 25%
• Within-host Dynamics 25%
• Murine Astrovirus 25%
• Transmission Route 25%
• Across Species 25%
• Evolutionary Events 25%
• Limited Diversity 25%
• Bottleneck Event 25%

Immunology and Microbiology

• Virus 100%
• Virus Transmission 100%
• Picornaviridae 100%
• Purifying Selection 100%
• Rodentia 100%
• Virus Evolution 66%
• Peromyscus 66%
• Next Generation Sequencing 33%
• Dynamics 33%
• Infectious Agent 33%
• RNA Sequence 33%
• Pet Animal 33%
• Population Structure 33%
• Mus musculus 33%
• Astroviridae 33%
• Kobuvirus 33%
• Peromyscus maniculatus 33%
• Coronavirus 33%