Experimental and computational studies on interrupted Nazarov reactions: Exploration of umpolung reactivity at the α-carbon of cyclopentanones

Keyphrases

• Computational Study 100%
• Umpolung Reaction 100%
• Nazarov Reaction 100%
• Nazarov 100%
• Cyclopentanone 100%
• Oxyallyl 66%
• Two-component 33%
• Furan 33%
• Carbon-carbon Bond Formation 33%
• Nucleophilic 33%
• Allyl 33%
• Cycloaddition 33%
• Alkynyl 33%
• Bicyclic Systems 33%
• Formal Cycloaddition 33%
• Diastereoselectivity 33%
• Heteroaryl 33%
• Reaction Sequence 33%
• Reaction Parameters 33%
• Reaction Pattern 33%
• Nucleophilic Addition 33%
• DFT Computations 33%
• Carbon nucleophiles 33%
• Bridged Bicyclic 33%
• Divinyl Ketone 33%
• One-terminal 33%
• Umpolung 33%
• Electrocyclization 33%
• Domino Reactions 33%
• Quaternary Centers 33%

Chemistry

• Umpolung 100%
• Nazarov Cyclization 100%
• Cyclopentanone 100%
• Cycloaddition 40%
• Density Functional Theory 20%
• Ketones 20%
• Diastereoselectivity 20%
• Reaction Parameter 20%
• Allyl Group 20%
• Domino Reaction 20%
• Heteroaryl Group 20%
• Furan 20%
• Nucleophile 20%
• formation 20%
• Nucleophilic Addition 20%