Experimental and computational studies of growth cone motility in nerve growth and regeneration

Helen M. Buettner, Stacy S. Hawkins-Gwydir, David J. Odde, Hsin Chien Tai, Deanna M. Thompson

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This study has experimentally measured growth cone motility under several conditions involving the extracellular matrix substrates, collagen and laminin, in uniform or patterned arrangements to provide insight into the mechanisms by which the growth cone guides axonal extension in the embryo and thus mechanisms that may be exploited to enhance nerve regeneration. Moreover, a simulation model of growth cone dynamics is also developed to help quantitate these effects.

Original languageEnglish (US)
Title of host publicationAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
PublisherASME
Pages157-158
Number of pages2
Volume29
StatePublished - Jan 1 1995
EventProceedings of the 1995 Bioengineering Conference - Beever Creek, CO, USA
Duration: Jun 28 1995Jul 2 1995

Other

OtherProceedings of the 1995 Bioengineering Conference
CityBeever Creek, CO, USA
Period6/28/957/2/95

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    Buettner, H. M., Hawkins-Gwydir, S. S., Odde, D. J., Tai, H. C., & Thompson, D. M. (1995). Experimental and computational studies of growth cone motility in nerve growth and regeneration. In American Society of Mechanical Engineers, Bioengineering Division (Publication) BED (Vol. 29, pp. 157-158). ASME.