Experimental and computational studies of growth cone motility in nerve growth and regeneration

Helen M. Buettner; Stacy S. Hawkins-Gwydir; David J. Odde; Hsin Chien Tai; Deanna M. Thompson

Experimental and computational studies of growth cone motility in nerve growth and regeneration

Helen M. Buettner, Stacy S. Hawkins-Gwydir, David J. Odde, Hsin Chien Tai, Deanna M. Thompson

Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

This study has experimentally measured growth cone motility under several conditions involving the extracellular matrix substrates, collagen and laminin, in uniform or patterned arrangements to provide insight into the mechanisms by which the growth cone guides axonal extension in the embryo and thus mechanisms that may be exploited to enhance nerve regeneration. Moreover, a simulation model of growth cone dynamics is also developed to help quantitate these effects.

Original language	English (US)
Title of host publication	American Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Publisher	ASME
Pages	157-158
Number of pages	2
Volume	29
State	Published - Jan 1 1995
Event	Proceedings of the 1995 Bioengineering Conference - Beever Creek, CO, USA Duration: Jun 28 1995 → Jul 2 1995

Other

Other	Proceedings of the 1995 Bioengineering Conference
City	Beever Creek, CO, USA
Period	6/28/95 → 7/2/95

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Experimental and computational studies of growth cone motility in nerve growth and regeneration. / Buettner, Helen M.; Hawkins-Gwydir, Stacy S.; Odde, David J. et al.
American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. Vol. 29 ASME, 1995. p. 157-158.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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abstract = "This study has experimentally measured growth cone motility under several conditions involving the extracellular matrix substrates, collagen and laminin, in uniform or patterned arrangements to provide insight into the mechanisms by which the growth cone guides axonal extension in the embryo and thus mechanisms that may be exploited to enhance nerve regeneration. Moreover, a simulation model of growth cone dynamics is also developed to help quantitate these effects.",

author = "Buettner, {Helen M.} and Hawkins-Gwydir, {Stacy S.} and Odde, {David J.} and Tai, {Hsin Chien} and Thompson, {Deanna M.}",

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AU - Tai, Hsin Chien

AU - Thompson, Deanna M.

PY - 1995/1/1

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N2 - This study has experimentally measured growth cone motility under several conditions involving the extracellular matrix substrates, collagen and laminin, in uniform or patterned arrangements to provide insight into the mechanisms by which the growth cone guides axonal extension in the embryo and thus mechanisms that may be exploited to enhance nerve regeneration. Moreover, a simulation model of growth cone dynamics is also developed to help quantitate these effects.

AB - This study has experimentally measured growth cone motility under several conditions involving the extracellular matrix substrates, collagen and laminin, in uniform or patterned arrangements to provide insight into the mechanisms by which the growth cone guides axonal extension in the embryo and thus mechanisms that may be exploited to enhance nerve regeneration. Moreover, a simulation model of growth cone dynamics is also developed to help quantitate these effects.

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M3 - Conference contribution

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PB - ASME

T2 - Proceedings of the 1995 Bioengineering Conference

Y2 - 28 June 1995 through 2 July 1995

ER -

Experimental and computational studies of growth cone motility in nerve growth and regeneration

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