Expansion and Activation of Human Natural Killer Cells for Autologous Therapy

Jeffrey S Miller, Catherine Verfaillie, Philip B Mc Glave

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Ex vivo depletion of lymphocytes has been used to decrease the incidence of acute graft-versus-host disease following the allogeneic bone marrow transplantation. Many depletion techniques also remove natural killer (NK) cells that may mediate a beneficial graft-versus-leukemia effect. In this paper we review our studies on ex vivo expansion and activation of NK cells for use in the therapy of chronic myelogenous leukemia.

Original languageEnglish (US)
Pages (from-to)71-74
Number of pages4
JournalJournal of Hematotherapy
Volume3
Issue number1
DOIs
StatePublished - Jan 1 1994

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