Abstract
We've got talent: New enzymes with novel reactivity are constantly added to the enzyme toolbox as exemplified by the berberine bridge enzyme (BBE). Analogues of 2, which are bioactive, have been successfully made from analogues of 1 using BBE. Such new enzymes hold the promise of convenient synthesis of potentially useful nonnatural products.
Original language | English (US) |
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Pages (from-to) | 7476-7478 |
Number of pages | 3 |
Journal | Angewandte Chemie - International Edition |
Volume | 50 |
Issue number | 33 |
DOIs | |
State | Published - Aug 8 2011 |
Keywords
- biocatalysis
- drug discovery
- enzyme models
- enzymes
- synthetic methods