Expanding the enzyme toolbox for biocatalysis

Research output: Contribution to journalArticle

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Abstract

We've got talent: New enzymes with novel reactivity are constantly added to the enzyme toolbox as exemplified by the berberine bridge enzyme (BBE). Analogues of 2, which are bioactive, have been successfully made from analogues of 1 using BBE. Such new enzymes hold the promise of convenient synthesis of potentially useful nonnatural products.

Original languageEnglish (US)
Pages (from-to)7476-7478
Number of pages3
JournalAngewandte Chemie - International Edition
Volume50
Issue number33
DOIs
StatePublished - Aug 8 2011

Keywords

  • biocatalysis
  • drug discovery
  • enzyme models
  • enzymes
  • synthetic methods

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