Expanding a First-Order Logic Mitigation Framework to Handle Multimorbid Patient Preferences

Martin Michalowski, Szymon Wilk, Daniela Rosu, Mounira Kezadri, Wojtek Michalowski, Marc Carrier

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The increasing prevalence of multimorbidity is a challenge for physicians who have to manage a constantly growing number of patients with simultaneous diseases. Adding to this challenge is the need to incorporate patient preferences as key components of the care process, thanks in part to the emergence of personalized and participatory medicine. In our previous work we proposed a framework employing first order logic to represent clinical practice guidelines (CPGs) and to mitigate possible adverse interactions when concurrently applying multiple CPGs to a multimorbid patient. In this paper, we describe extensions to our methodological framework that (1) broaden our definition of revision operators to support required and desired types of revisions defined in secondary knowledge sources, and (2) expand the mitigation algorithm to apply revisions based on their type. We illustrate the capabilities of the expanded framework using a clinical case study of a multimorbid patient with stable cardiac artery disease who suffers a sudden onset of deep vein thrombosis.

Original languageEnglish (US)
Pages (from-to)895-904
Number of pages10
JournalAMIA ... Annual Symposium proceedings. AMIA Symposium
Volume2015
StatePublished - Jan 1 2015

Fingerprint

Patient Preference
Practice Guidelines
Precision Medicine
Venous Thrombosis
Comorbidity
Heart Diseases
Arteries
Physicians

Cite this

Expanding a First-Order Logic Mitigation Framework to Handle Multimorbid Patient Preferences. / Michalowski, Martin; Wilk, Szymon; Rosu, Daniela; Kezadri, Mounira; Michalowski, Wojtek; Carrier, Marc.

In: AMIA ... Annual Symposium proceedings. AMIA Symposium, Vol. 2015, 01.01.2015, p. 895-904.

Research output: Contribution to journalArticle

Michalowski, Martin ; Wilk, Szymon ; Rosu, Daniela ; Kezadri, Mounira ; Michalowski, Wojtek ; Carrier, Marc. / Expanding a First-Order Logic Mitigation Framework to Handle Multimorbid Patient Preferences. In: AMIA ... Annual Symposium proceedings. AMIA Symposium. 2015 ; Vol. 2015. pp. 895-904.
@article{cff7f9e2ad4b4be9911923b876cc5bba,
title = "Expanding a First-Order Logic Mitigation Framework to Handle Multimorbid Patient Preferences",
abstract = "The increasing prevalence of multimorbidity is a challenge for physicians who have to manage a constantly growing number of patients with simultaneous diseases. Adding to this challenge is the need to incorporate patient preferences as key components of the care process, thanks in part to the emergence of personalized and participatory medicine. In our previous work we proposed a framework employing first order logic to represent clinical practice guidelines (CPGs) and to mitigate possible adverse interactions when concurrently applying multiple CPGs to a multimorbid patient. In this paper, we describe extensions to our methodological framework that (1) broaden our definition of revision operators to support required and desired types of revisions defined in secondary knowledge sources, and (2) expand the mitigation algorithm to apply revisions based on their type. We illustrate the capabilities of the expanded framework using a clinical case study of a multimorbid patient with stable cardiac artery disease who suffers a sudden onset of deep vein thrombosis.",
author = "Martin Michalowski and Szymon Wilk and Daniela Rosu and Mounira Kezadri and Wojtek Michalowski and Marc Carrier",
year = "2015",
month = "1",
day = "1",
language = "English (US)",
volume = "2015",
pages = "895--904",
journal = "AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium",
issn = "1559-4076",
publisher = "American Medical Informatics Association",

}

TY - JOUR

T1 - Expanding a First-Order Logic Mitigation Framework to Handle Multimorbid Patient Preferences

AU - Michalowski, Martin

AU - Wilk, Szymon

AU - Rosu, Daniela

AU - Kezadri, Mounira

AU - Michalowski, Wojtek

AU - Carrier, Marc

PY - 2015/1/1

Y1 - 2015/1/1

N2 - The increasing prevalence of multimorbidity is a challenge for physicians who have to manage a constantly growing number of patients with simultaneous diseases. Adding to this challenge is the need to incorporate patient preferences as key components of the care process, thanks in part to the emergence of personalized and participatory medicine. In our previous work we proposed a framework employing first order logic to represent clinical practice guidelines (CPGs) and to mitigate possible adverse interactions when concurrently applying multiple CPGs to a multimorbid patient. In this paper, we describe extensions to our methodological framework that (1) broaden our definition of revision operators to support required and desired types of revisions defined in secondary knowledge sources, and (2) expand the mitigation algorithm to apply revisions based on their type. We illustrate the capabilities of the expanded framework using a clinical case study of a multimorbid patient with stable cardiac artery disease who suffers a sudden onset of deep vein thrombosis.

AB - The increasing prevalence of multimorbidity is a challenge for physicians who have to manage a constantly growing number of patients with simultaneous diseases. Adding to this challenge is the need to incorporate patient preferences as key components of the care process, thanks in part to the emergence of personalized and participatory medicine. In our previous work we proposed a framework employing first order logic to represent clinical practice guidelines (CPGs) and to mitigate possible adverse interactions when concurrently applying multiple CPGs to a multimorbid patient. In this paper, we describe extensions to our methodological framework that (1) broaden our definition of revision operators to support required and desired types of revisions defined in secondary knowledge sources, and (2) expand the mitigation algorithm to apply revisions based on their type. We illustrate the capabilities of the expanded framework using a clinical case study of a multimorbid patient with stable cardiac artery disease who suffers a sudden onset of deep vein thrombosis.

UR - http://www.scopus.com/inward/record.url?scp=85007464732&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85007464732&partnerID=8YFLogxK

M3 - Article

C2 - 26958226

AN - SCOPUS:85007464732

VL - 2015

SP - 895

EP - 904

JO - AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium

JF - AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium

SN - 1559-4076

ER -