Executive summary of IPITA-TTS opinion leaders report on the future of b-cell replacement

James F. Markmann; Stephen T. Bartlett; Paul Johnson; Olle Korsgren; Bernhard J. Hering; David Scharp; Thomas W H Kay; Jonathan Bromberg; Jon S. Odorico; Gordon C. Weir; Nancy Bridges; Raja Kandaswamy; Peter Stock; Peter Friend; Mitsukazu Gotoh; David K C Cooper; Chung Gyu Park; Philip J. O'Connell; Cherie Stabler; Shinichi Matsumoto; Barbara Ludwig; Pratik Choudhary; Boris Khovatchev; Michael R. Rickels; Megan Sykes; Kathryn Wood; Kristy Kraemer; Albert Hwa; Edward Stanley; Camillo Ricordi; Mark Zimmerman; Julia Greenstein; Eduard Montanya; Timo Otonkoski

doi:10.1097/TP.0000000000001054

Executive summary of IPITA-TTS opinion leaders report on the future of b-cell replacement

James F. Markmann, Stephen T. Bartlett, Paul Johnson, Olle Korsgren, Bernhard J. Hering, David Scharp, Thomas W H Kay, Jonathan Bromberg, Jon S. Odorico, Gordon C. Weir, Nancy Bridges, Raja Kandaswamy, Peter Stock, Peter Friend, Mitsukazu Gotoh, David K C Cooper, Chung Gyu Park, Philip J. O'Connell, Cherie Stabler, Shinichi MatsumotoBarbara Ludwig, Pratik Choudhary, Boris Khovatchev, Michael R. Rickels, Megan Sykes, Kathryn Wood, Kristy Kraemer, Albert Hwa, Edward Stanley, Camillo Ricordi, Mark Zimmerman, Julia Greenstein, Eduard Montanya, Timo Otonkoski

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Abstract

The International Pancreas and Islet Transplant Association (IPITA), in conjunctionwith the Transplantation Society (TTS), convened a workshop to consider the future of pancreas and islet transplantation in the context of potential competing technologies that are under development, including the artificial pancreas, transplantation tolerance, xenotransplantation, encapsulation, stem cell derived beta cells, beta cell proliferation, and endogenous regeneration. Separate workgroups for each topic and then the collective group reviewed the state of the art, hurdles to application, and proposed research agenda for each therapy that would allow widespread application. Herein we present the executive summary of this workshop that focuses on obstacles to application and the research agenda to overcome them; the full length article with detailed background for each topic is published as an online supplement to Transplantation.

Original language	English (US)
Pages (from-to)	e25-e31
Journal	Transplantation
Volume	100
Issue number	7
DOIs	https://doi.org/10.1097/TP.0000000000001054
State	Published - Jun 21 2016

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© 2016 Wolters Kluwer Health, Inc. All rights reserved.

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Markmann, J. F., Bartlett, S. T., Johnson, P., Korsgren, O., Hering, B. J., Scharp, D., Kay, T. W. H., Bromberg, J., Odorico, J. S., Weir, G. C., Bridges, N., Kandaswamy, R., Stock, P., Friend, P., Gotoh, M., Cooper, D. K. C., Park, C. G., O'Connell, P. J., Stabler, C., ... Otonkoski, T. (2016). Executive summary of IPITA-TTS opinion leaders report on the future of b-cell replacement. Transplantation, 100(7), e25-e31. https://doi.org/10.1097/TP.0000000000001054

Markmann, JF, Bartlett, ST, Johnson, P, Korsgren, O, Hering, BJ, Scharp, D, Kay, TWH, Bromberg, J, Odorico, JS, Weir, GC, Bridges, N, Kandaswamy, R, Stock, P, Friend, P, Gotoh, M, Cooper, DKC, Park, CG, O'Connell, PJ, Stabler, C, Matsumoto, S, Ludwig, B, Choudhary, P, Khovatchev, B, Rickels, MR, Sykes, M, Wood, K, Kraemer, K, Hwa, A, Stanley, E, Ricordi, C, Zimmerman, M, Greenstein, J, Montanya, E & Otonkoski, T 2016, 'Executive summary of IPITA-TTS opinion leaders report on the future of b-cell replacement', Transplantation, vol. 100, no. 7, pp. e25-e31. https://doi.org/10.1097/TP.0000000000001054

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abstract = "The International Pancreas and Islet Transplant Association (IPITA), in conjunctionwith the Transplantation Society (TTS), convened a workshop to consider the future of pancreas and islet transplantation in the context of potential competing technologies that are under development, including the artificial pancreas, transplantation tolerance, xenotransplantation, encapsulation, stem cell derived beta cells, beta cell proliferation, and endogenous regeneration. Separate workgroups for each topic and then the collective group reviewed the state of the art, hurdles to application, and proposed research agenda for each therapy that would allow widespread application. Herein we present the executive summary of this workshop that focuses on obstacles to application and the research agenda to overcome them; the full length article with detailed background for each topic is published as an online supplement to Transplantation.",

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AU - Hering, Bernhard J.

AU - Scharp, David

AU - Kay, Thomas W H

AU - Bromberg, Jonathan

AU - Odorico, Jon S.

AU - Weir, Gordon C.

AU - Bridges, Nancy

AU - Kandaswamy, Raja

AU - Stock, Peter

AU - Friend, Peter

AU - Gotoh, Mitsukazu

AU - Cooper, David K C

AU - Park, Chung Gyu

AU - O'Connell, Philip J.

AU - Stabler, Cherie

AU - Matsumoto, Shinichi

AU - Ludwig, Barbara

AU - Choudhary, Pratik

AU - Khovatchev, Boris

AU - Rickels, Michael R.

AU - Sykes, Megan

AU - Wood, Kathryn

AU - Kraemer, Kristy

AU - Hwa, Albert

AU - Stanley, Edward

AU - Ricordi, Camillo

AU - Zimmerman, Mark

AU - Greenstein, Julia

AU - Montanya, Eduard

AU - Otonkoski, Timo

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Executive summary of IPITA-TTS opinion leaders report on the future of b-cell replacement

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