Executive functioning deficits in preschool children with Fetal Alcohol Spectrum Disorders

Anita J. Fuglestad, Marisa L. Whitley, Stephanie M Carlson, Christopher J Boys, Judith K Eckerle, Birgit A. Fink, Jeffrey R Wozniak

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Executive function (EF) deficit is a hallmark of Fetal Alcohol Spectrum Disorders (FASD), but the vast majority of available evidence comes from school-age children and adolescents. Very little is known about EF during the critical developmental period prior to 6 years of age in FASD. We evaluated EF in 39 children with FASD (3.0-5.5 years) and a comparison group of 50 age-matched, nonexposed controls. Measures included the EF Scale for Early Childhood and a Delay of Gratification task. Compared to age-matched controls, preschool children with FASD had impairments on the EF Scale and showed more impulsivity on the Delay of Gratification task. To confirm the EF Scale finding, FASD group performance was compared to a separate normative dataset (N = 1,400). Those with FASD performed below normal (M = -0.57, SD = 0.92). Within the FASD group, IQ was correlated with the EF Scale (partial r =.60, p =.001) and Delay of Gratification (partial r =.58, p =.005). EF Scale performance did not differ significantly across levels of FASD severity (fetal alcohol syndrome [FAS], partial FAS, or alcohol-related neurobehavioral disorder [ARND]). However, compared to normative data, those with FAS had the largest deficits (M = -0.91 SD from the mean, SE = 0.23), followed by partial FAS (M = -0.66 SD from the mean, SE = 0.26), then ARND (M = -0.36 SD from the mean, SE = 0.20). These novel data show that EF deficits manifest well before the age of 6 years in children with FASD, that they occur across the spectrum, and that EF may be most impaired in children with more severe forms of FASD and/or lower IQs.

Original languageEnglish (US)
Pages (from-to)716-731
Number of pages16
JournalChild Neuropsychology
Volume21
Issue number6
DOIs
StatePublished - Nov 2 2015

Fingerprint

Fetal Alcohol Spectrum Disorders
Preschool Children
Executive Function
Alcohol-Related Disorders
Impulsive Behavior

Keywords

  • Delay of Gratification
  • Executive function
  • Fetal alcohol spectrum disorders (FAS, FASD)
  • Prenatal alcohol exposure

Cite this

Executive functioning deficits in preschool children with Fetal Alcohol Spectrum Disorders. / Fuglestad, Anita J.; Whitley, Marisa L.; Carlson, Stephanie M; Boys, Christopher J; Eckerle, Judith K; Fink, Birgit A.; Wozniak, Jeffrey R.

In: Child Neuropsychology, Vol. 21, No. 6, 02.11.2015, p. 716-731.

Research output: Contribution to journalArticle

@article{3d848bd705c6430eb98f21feef013fe0,
title = "Executive functioning deficits in preschool children with Fetal Alcohol Spectrum Disorders",
abstract = "Executive function (EF) deficit is a hallmark of Fetal Alcohol Spectrum Disorders (FASD), but the vast majority of available evidence comes from school-age children and adolescents. Very little is known about EF during the critical developmental period prior to 6 years of age in FASD. We evaluated EF in 39 children with FASD (3.0-5.5 years) and a comparison group of 50 age-matched, nonexposed controls. Measures included the EF Scale for Early Childhood and a Delay of Gratification task. Compared to age-matched controls, preschool children with FASD had impairments on the EF Scale and showed more impulsivity on the Delay of Gratification task. To confirm the EF Scale finding, FASD group performance was compared to a separate normative dataset (N = 1,400). Those with FASD performed below normal (M = -0.57, SD = 0.92). Within the FASD group, IQ was correlated with the EF Scale (partial r =.60, p =.001) and Delay of Gratification (partial r =.58, p =.005). EF Scale performance did not differ significantly across levels of FASD severity (fetal alcohol syndrome [FAS], partial FAS, or alcohol-related neurobehavioral disorder [ARND]). However, compared to normative data, those with FAS had the largest deficits (M = -0.91 SD from the mean, SE = 0.23), followed by partial FAS (M = -0.66 SD from the mean, SE = 0.26), then ARND (M = -0.36 SD from the mean, SE = 0.20). These novel data show that EF deficits manifest well before the age of 6 years in children with FASD, that they occur across the spectrum, and that EF may be most impaired in children with more severe forms of FASD and/or lower IQs.",
keywords = "Delay of Gratification, Executive function, Fetal alcohol spectrum disorders (FAS, FASD), Prenatal alcohol exposure",
author = "Fuglestad, {Anita J.} and Whitley, {Marisa L.} and Carlson, {Stephanie M} and Boys, {Christopher J} and Eckerle, {Judith K} and Fink, {Birgit A.} and Wozniak, {Jeffrey R}",
year = "2015",
month = "11",
day = "2",
doi = "10.1080/09297049.2014.933792",
language = "English (US)",
volume = "21",
pages = "716--731",
journal = "Child Neuropsychology",
issn = "0929-7049",
publisher = "Psychology Press Ltd",
number = "6",

}

TY - JOUR

T1 - Executive functioning deficits in preschool children with Fetal Alcohol Spectrum Disorders

AU - Fuglestad, Anita J.

AU - Whitley, Marisa L.

AU - Carlson, Stephanie M

AU - Boys, Christopher J

AU - Eckerle, Judith K

AU - Fink, Birgit A.

AU - Wozniak, Jeffrey R

PY - 2015/11/2

Y1 - 2015/11/2

N2 - Executive function (EF) deficit is a hallmark of Fetal Alcohol Spectrum Disorders (FASD), but the vast majority of available evidence comes from school-age children and adolescents. Very little is known about EF during the critical developmental period prior to 6 years of age in FASD. We evaluated EF in 39 children with FASD (3.0-5.5 years) and a comparison group of 50 age-matched, nonexposed controls. Measures included the EF Scale for Early Childhood and a Delay of Gratification task. Compared to age-matched controls, preschool children with FASD had impairments on the EF Scale and showed more impulsivity on the Delay of Gratification task. To confirm the EF Scale finding, FASD group performance was compared to a separate normative dataset (N = 1,400). Those with FASD performed below normal (M = -0.57, SD = 0.92). Within the FASD group, IQ was correlated with the EF Scale (partial r =.60, p =.001) and Delay of Gratification (partial r =.58, p =.005). EF Scale performance did not differ significantly across levels of FASD severity (fetal alcohol syndrome [FAS], partial FAS, or alcohol-related neurobehavioral disorder [ARND]). However, compared to normative data, those with FAS had the largest deficits (M = -0.91 SD from the mean, SE = 0.23), followed by partial FAS (M = -0.66 SD from the mean, SE = 0.26), then ARND (M = -0.36 SD from the mean, SE = 0.20). These novel data show that EF deficits manifest well before the age of 6 years in children with FASD, that they occur across the spectrum, and that EF may be most impaired in children with more severe forms of FASD and/or lower IQs.

AB - Executive function (EF) deficit is a hallmark of Fetal Alcohol Spectrum Disorders (FASD), but the vast majority of available evidence comes from school-age children and adolescents. Very little is known about EF during the critical developmental period prior to 6 years of age in FASD. We evaluated EF in 39 children with FASD (3.0-5.5 years) and a comparison group of 50 age-matched, nonexposed controls. Measures included the EF Scale for Early Childhood and a Delay of Gratification task. Compared to age-matched controls, preschool children with FASD had impairments on the EF Scale and showed more impulsivity on the Delay of Gratification task. To confirm the EF Scale finding, FASD group performance was compared to a separate normative dataset (N = 1,400). Those with FASD performed below normal (M = -0.57, SD = 0.92). Within the FASD group, IQ was correlated with the EF Scale (partial r =.60, p =.001) and Delay of Gratification (partial r =.58, p =.005). EF Scale performance did not differ significantly across levels of FASD severity (fetal alcohol syndrome [FAS], partial FAS, or alcohol-related neurobehavioral disorder [ARND]). However, compared to normative data, those with FAS had the largest deficits (M = -0.91 SD from the mean, SE = 0.23), followed by partial FAS (M = -0.66 SD from the mean, SE = 0.26), then ARND (M = -0.36 SD from the mean, SE = 0.20). These novel data show that EF deficits manifest well before the age of 6 years in children with FASD, that they occur across the spectrum, and that EF may be most impaired in children with more severe forms of FASD and/or lower IQs.

KW - Delay of Gratification

KW - Executive function

KW - Fetal alcohol spectrum disorders (FAS, FASD)

KW - Prenatal alcohol exposure

UR - http://www.scopus.com/inward/record.url?scp=84940792924&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84940792924&partnerID=8YFLogxK

U2 - 10.1080/09297049.2014.933792

DO - 10.1080/09297049.2014.933792

M3 - Article

C2 - 25011516

AN - SCOPUS:84940792924

VL - 21

SP - 716

EP - 731

JO - Child Neuropsychology

JF - Child Neuropsychology

SN - 0929-7049

IS - 6

ER -