EXCITOTOXICITY AS A STOCHASTIC PROCESS

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Abstract

1. Neuronal death following excitotoxic insult appears to be a stochastic process involving transition through an intermediate biochemical state. 2. Hydrogen ion accumulation in the hours after toxic glutamate exposure may indicate that this transition has occurred.

Original languageEnglish (US)
Pages (from-to)297-298
Number of pages2
JournalClinical and Experimental Pharmacology and Physiology
Volume22
Issue number4
DOIs
StatePublished - Apr 1995

Keywords

  • excitotoxicity
  • giutamnte
  • hippocampal
  • intracellular pH
  • ischaemia
  • neurotoxicity.

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