Ex vivo-transduced autologous skin fibroblasts expressing human Lim mineralization protein-3 efficiently form new bone in animal models

Keyphrases

• Bone Formation 100%
• New Bone 100%
• Skin Fibroblasts 100%
• Dermal Fibroblasts 100%
• Autologous Dermal Fibroblasts 100%
• X-ray 50%
• Histology 50%
• Clinically Significant 50%
• Three-dimensional (3D) 50%
• Healing 50%
• Gene Therapy 50%
• Gene Transfer 50%
• Clinical Application 50%
• Biomaterials 50%
• Genetic Modification 50%
• New Bone Formation 50%
• Rodents 50%
• Therapy Approaches 50%
• Bone Healing 50%
• Microcomputed Tomography 50%
• Triceps 50%
• Defect Model 50%
• Collagen Matrix 50%
• Critical Size Defect 50%
• Mandibular Bone 50%
• Ectopic Bone Formation 50%
• Positive Regulator 50%
• Relevant Genes 50%
• Osteoblast Differentiation 50%
• Autologous Implantation 50%
• Hydroxyapatite Collagen 50%
• Paravertebral muscle 50%
• Osteogenic Factor 50%

Medicine and Dentistry

• Ex Vivo 100%
• Mineralization 100%
• Synapsin II 100%
• Skin Fibroblast 100%
• Ossification 66%
• Fibroblast 66%
• Gene Therapy 16%
• Gene Transfer 16%
• X-Ray Microtomography 16%
• Hydroxylapatite 16%
• Biocompatible Material 16%
• Osteoblast 16%
• Critical-Size Bone Defect 16%

Biochemistry, Genetics and Molecular Biology

• Animal Models 100%
• Mineralization 100%
• Fibroblast 100%
• Ossification 66%
• X Ray 16%
• Gene Therapy 16%
• Osteoblast 16%
• Micro-Computed Tomography 16%