Evolving Science on Cardiovascular Disease Among Hispanic/Latino Adults: JACC International

Amber Pirzada, Jianwen Cai, Gerardo Heiss, Daniela Sotres-Alvarez, Linda C. Gallo, Marston E. Youngblood, M. Larissa Avilés-Santa, Hector M. González, Carmen R. Isasi, Robert Kaplan, John Kunz, James P. Lash, David J. Lee, Maria M. Llabre, Frank J. Penedo, Carlos J. Rodriguez, Neil Schneiderman, Tamar Sofer, Gregory A. Talavera, Bharat ThyagarajanSylvia Wassertheil-Smoller, Martha L. Daviglus

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations


The landmark, multicenter HCHS/SOL (Hispanic Community Health Study/Study of Latinos) is the largest, most comprehensive, longitudinal community-based cohort study to date of diverse Hispanic/Latino persons in the United States. The HCHS/SOL aimed to address the dearth of comprehensive data on risk factors for cardiovascular disease (CVD) and other chronic diseases in this population and has expanded considerably in scope since its inception. This paper describes the aims/objectives and data collection of the HCHS/SOL and its ancillary studies to date and highlights the critical and sizable contributions made by the study to understanding the prevalence of and changes in CVD risk/protective factors and the burden of CVD and related chronic conditions among adults of diverse Hispanic/Latino backgrounds. The continued follow-up of this cohort will allow in-depth investigations on cardiovascular and pulmonary outcomes in this population, and data from the ongoing ancillary studies will facilitate generation of new hypotheses and study questions.

Original languageEnglish (US)
Pages (from-to)1505-1520
Number of pages16
JournalJournal of the American College of Cardiology
Issue number15
StatePublished - Apr 18 2023

Bibliographical note

Publisher Copyright:
© 2023 American College of Cardiology Foundation


  • Hispanic/Latino
  • cardiovascular disease
  • cohort study
  • study design


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