Evolutionary landscapes for complex selection.

Wright's principle of maximized mean viability is known to be violated in a number of biologically significant situations involving complex modes of selection, including epistasis, meiotic drive, organismal interaction, fertility selection, selective differences between the sexes, and gametic selection. In this paper, Lewontin's (1958) method of weights is extended to derive a very general maximization principle for general one-locus, two-allele deterministic selection models. New maximization principles are developed for the cases of meiotic drive and gametic selection, thereby defining evolutionary landscapes.-Author