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Evolution of accumulated energy predicts seizures in mesial temporal lobe epilepsy

  • B. Litt
  • , R. Esteller
  • , M. D'Alessandro
  • , J. Echauz
  • , R. Shor
  • , C. Bowen
  • , G. Vachtsevanos

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We present a promising feature for predicting epileptic seizures (Sz) 20 to 50 minutes prior to EEG onset. We calculated accumulated energy (AE) in the region of Sz onset for 13 pre-Sz and 24 baseline recordings obtained from intracranial EEG (IEEG) recordings in 3 patients with mesial temporal lobe epilepsy (MTLE) during evaluation for epilepsy surgery. In all patients pre-Sz AE deviated in a statistically significant fashion from trajectories calculated during periods far removed from Sz. Patterns of deviation differed between sleep and awake states in all patients. Our results indicate that AE is a useful feature for predicting Sz in patients with MTLE, and may compliment other features for Sz prediction with different time horizons.

Original languageEnglish (US)
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
PublisherIEEE
Pages440
Number of pages1
ISBN (Print)0780356756
StatePublished - 1999
Externally publishedYes
EventProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) - Atlanta, GA, USA
Duration: Oct 13 1999 → Oct 16 1999

Publication series

NameAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume1
ISSN (Print)0589-1019

Other

OtherProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS)
CityAtlanta, GA, USA
Period10/13/99 → 10/16/99

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